Remodeling of soft tissues due to cell activity

  • Umbauprozess von Weichteilgeweben infolge zellulärer Aktivität

Yi, Jeong-Hun; Weichert, Dieter (Thesis advisor)

Aachen : Publikationsserver der RWTH Aachen University (2013)
Dissertation / PhD Thesis

Aachen, Techn. Hochsch., Diss., 2013


This work deals with the analysis of the modified material properties of cellular tissues. For the experimental study, cell-seeded condensed collagen gel specimens were stimulated mechanically in bioreactors for four weeks. To follow the Young's modulus modification (remodeling), a compression test was performed every week. A constitutive equation is proposed for the remodeling effect of the cellular tissue, and a remodeling velocity parameter is identified.